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From SSRIs to Psilocybin: A Shift in Feeling

As psilocybin-assisted healing becomes more accessible, one question comes up again and again: Can I take psilocybin if I’m on antidepressants like SSRIs? The short answer is: yes, you can. But it may affect how psilocybin works—and it may also raise deeper questions about what kind of healing you’re after.

In this post, we’ll explore how SSRIs and psilocybin interact, what the research says, and why some people are beginning to explore psychedelics as an alternative to long-term pharmaceutical treatment.

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